U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1 - 10 of 14 results

Drospirenone (INN, USAN), also known as 1,2-dihydrospirorenone, is a steroidal progestin of the spirolactone group. Drospirenone binds strongly to the progesterone receptor (PR) and mineralocorticoid receptor (MR), with lower affinity, to the androgen receptor (AR), and very low affinity for the glucocorticoid receptor (GR). Drospirenone is an ingredient in some birth control pills and hormone replacement therapy. In combination with ethinylestradiol it is used as contraception, and for women who want contraception it is also approved by the U.S. Food and Drug Administration (FDA) to treat vasomotor symptoms due to menopause.It is sold as a combined oral contraceptive under the brand names Yasmin (US, EU, Latin America), Jasmine (France), Yarina (Russia) in a dosage containing drospirenone 3 mg/ethinylestradiol 30 µg. In the United States, Bayer Schering released a pill based on Yasmin with the B vitamin folate (B9), which is marketed under the names Safyral and Beyaz.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Drospirenone acid is a metabolite of drospirenone, one of the two main metabolites found in human plasma. Drospirenone is a synthetic progestational compound used as a component of oral contraceptive in combination with ethinyl estradiol (YASMIN®) or ethinyl estradiol/levomefolate calcium (BEYAZ®).
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

17-epidrospirenone is an epimer of drospirenone, considered to be impurity. Drospirenone is a synthetic progestational compound used as a component of oral contraceptive in combination with ethinyl estradiol.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

17-epidrospirenone is a derivative of drospirenone with a reversed configuration of the 17-spirolactone ring had no biological activity. Drospirenone impurity. Drospirenone is a synthetic progestational compound used as a component of oral contraceptive in combination with ethinyl estradiol.

Showing 1 - 10 of 14 results